Corticosteroid Production Rates in Strain 2 Guinea Pigs following L2C/NB Leukemia Transplantation1

نویسندگان

  • SHLOMO BURSTEIN
  • ELI M. NADEL
چکیده

Production rates of cortisol, 2a-hydroxycortisol, and 6/3hydroxycortisol were determined (by isotope dilution technics) in individual adult Strain 2 guinea pigs following transplantation of the guinea pig lymphoblastic leukemia I^C/NB. There was a statistically significant (P < 0.01, 0.02, and 0.01) 2.0-, 1.4-, and 1.9-fold higher production of cortisol, 2a-hydroxycortisol, and 6/3-hydroxycortisol, respectively, in leukemic guinea pigs in comparison with similarly treated controls. No statistical^-

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Corticosteroid production rates in strain 2 guinea pigs following L2C-NB leukemia transplantation.

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تاریخ انتشار 2006